Cationic 1,2,3 triazolium alkynes : components to enhance 1,4 regioselective azide rlkyne cycloaddition reactions

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dc.audience researchers es_MX
dc.contributor.author Yuri Reyes, 0000-0003-3945-2111
dc.contributor.other Monasterio Peiteado, Zaira
dc.contributor.other Sagartzazu Aizpurua, Maialen
dc.contributor.other Miranda, José I.
dc.contributor.other Aizpurua, Jesus M.
dc.coverage MX es_MX
dc.date.accessioned 2018-06-27T00:21:09Z
dc.date.available 2018-06-27T00:21:09Z
dc.date.issued 2016
dc.description 4-Alkynyl-1,2,3-triazolium cations undergo thermal [3 + 2] cycloaddition reactions with azides roughly 50- to 100-fold faster than comparable noncharged alkynes. Further, the reaction is highly 1,4-regioselective (dr up to 99:1) owing to the selective stabilization of 1,4-TS transition states via conjugative π-acceptor assistance of the alkyne triazolium ring. The novel cationic triazolium alkynes also accelerate the CuAAC reaction to provide bis(1,2,3-triazoles) in an “ultrafast” way (<5 min). es_MX
dc.format application/pdf es_MX
dc.identificador.materia 2 es_MX
dc.identifier.other http://dx.doi.org/10.1021/acs.orglett.6b00055
dc.identifier.uri http://hdl.handle.net/20.500.12222/158
dc.language eng es_MX
dc.publisher Universidad Autónoma Metropolitana. Unidad Lerma es_MX
dc.rights Attribution-NonCommercial-NoDerivatives 4.0 Internacional *
dc.rights.license info:eu-repo/semantics/openAccess *
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/4.0/ es_MX
dc.subject BIOLOGÍA Y QUÍMICA es_MX
dc.subject.keywords Cycloaddition Reactions es_MX
dc.subject.keywords Alkynes es_MX
dc.subject.keywords Dipolarophiles es_MX
dc.subject.keywords Synthesized es_MX
dc.title Cationic 1,2,3 triazolium alkynes : components to enhance 1,4 regioselective azide rlkyne cycloaddition reactions es_MX
dc.type preprint es_MX
dc.type.version info:eu-repo/semantics/publishedVersion es_MX
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