The microbiota-gut-brain axis: neurobehavioral correlates, health and sociality

dc.audience researchers es_MX
dc.contributor.author Gustavo Pacheco-Lopez, 0000-0002-3458-197X
dc.contributor.author Rina Gonzalez-Cervantes, 0000-0002-5617-2253
dc.contributor.other Montiel Castro, Augusto
dc.contributor.other Bravo Ruiseco, Gabriela
dc.coverage US es_MX
dc.date.accessioned 2018-05-30T23:20:08Z
dc.date.available 2018-05-30T23:20:08Z
dc.date.issued 2013
dc.description Recent data suggest that the human body is not such a neatly self-sufficient island after all. It is more like a super-complex ecosystem containing trillions of bacteria and other microorganisms that inhabit all our surfaces; skin, mouth, sexual organs, and specially intestines. It has recently become evident that such microbiota, specifically within the gut, can greatly influence many physiological parameters, including cognitive functions, such as learning, memory and decision making processes. Human microbiota is a diverse and dynamic ecosystem, which has evolved in a mutualistic relationship with its host. Ontogenetically, it is vertically inoculated from the mother during birth, established during the first year of life and during lifespan, horizontally transferred among relatives, mates or close community members. This micro-ecosystem serves the host by protecting it against pathogens, metabolizing complex lipids and polysaccharides that otherwise would be inaccessible nutrients, neutralizing drugs and carcinogens, modulating intestinal motility, and making visceral perception possible. It is now evident that the bidirectional signaling between the gastrointestinal tract and the brain, mainly through the vagus nerve, the so called “microbiota–gut–vagus–brain axis,” is vital for maintaining homeostasis and it may be also involved in the etiology of several metabolic and mental dysfunctions/disorders. Here we review evidence on the ability of the gut microbiota to communicate with the brain and thus modulate behavior, and also elaborate on the ethological and cultural strategies of human and non-human primates to select, transfer and eliminate microorganisms for selecting the commensal profile. es_MX
dc.format application/pdf es_MX
dc.identificador.materia 3 es_MX
dc.identifier.other https://doi.org/10.3389/fnint.2013.00070
dc.identifier.uri http://hdl.handle.net/20.500.12222/41
dc.language eng es_MX
dc.publisher Frontiers Media es_MX
dc.rights Attribution-NonCommercial-NoDerivatives 4.0 Internacional *
dc.rights.license info:eu-repo/semantics/openAccess es_MX
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/4.0/ es_MX
dc.source.other Frontiers in Integrative Neuroscience, vol.7 (2013) es_MX
dc.source.other ISSN: 1662-5145 es_MX
dc.subject MEDICINA Y CIENCIAS DE LA SALUD es_MX
dc.subject.keywords Microbiota–Gut–Brainaxis es_MX
dc.subject.keywords Neurobiology es_MX
dc.subject.keywords Psychoneuroimmunology es_MX
dc.subject.keywords Evolutionary Psychology es_MX
dc.subject.keywords Social Bonds es_MX
dc.subject.keywords Kissing es_MX
dc.title The microbiota-gut-brain axis: neurobehavioral correlates, health and sociality es_MX
dc.type article es_MX
dc.type.version info:eu-repo/semantics/publishedVersion es_MX
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